Creative Biolabs is always proud of providing
innovatively designed services to propel clients’ researches. Now we practice
this principle on membrane protein service
again. Unlike conventional over expression techniques with limiting features on
several aspects, Creative Biolabs offers different membrane protein expression
methods to fulfill the customers' demands.
The alternative expressions of membrane protein
make Creative Biolabs outstanding from peer companies:
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Cell-based Expression (Native Conformation)
Our innovative cell-based expression technologies
can best preserve the native conformation of membrane proteins. A wide range of
service is provided based on this technology for production, extraction,
solubilization, purification, stabilization and crystallization of functional
membrane proteins/antigens.
l Cell-free
Expression (Functional Membrane Protein)
The cell-free expression enables the embedding of
membrane proteins in liposomes (bilayer vehicles and planars) directly during
the translation step to allow the production of active
"ready-to-use"proteoliposomes.
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Virus-like Particles (VLPs)
Expression of viral envelope or capside proteins
results in self-assembly of virus-like particles (VLPs). A good possibility to
produce membrane proteins in correct functional conformational manner, is to
express these proteins in composition of VLPs. VLPs could be used for different
approaches, e.g. vaccine development, investigation of receptor functions,
screening of antibodies, for immunization and also for purification of
different membrane proteins.
Using these expression systems, we have
successfully expressed different types of membrane proteins such as GPCRs, ion
channels, porins, viral proteins, transporters, drug receptors, etc. In
addition, we provide a centralized area for application of expression and
scale-up production of membrane proteins, their purification and
characterization.
With our services based on innovative strategies,
we keep ourselves being updated all the time to work closely with our consumers
and meet their demands. We have been, and will always be committed on accelerating
our clients business via better performance .
This is written by Victoria, the editor of Creative Biolabs, a global
life science company that is excellent in providing proteinic custom service
through its complete system and wealth experienced staff team.
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