Monday, January 12, 2015

In Situ Hybridization – An Up-rising Star in the Field of Biology

In situ hybridization (ISH) may not be a new phrase for today’s Biological world. It has not been in this industry for long, but its promising future, without any doubt, is recognized by increasing biologists and institutions.

In situ hybridization (ISH) is a technology being made up of combinations of molecular biology, histochemistry and cytology. Gall from Yale University together with other biologists’ crossing the Xenopus laevis ribosomal genes with its oocyte and mapping the product in 1969, along with Buongiorno Nardell and Amaldi’s mapping the gene of the cell and tissue with isotope-labeled nucleic acid probe in 1970 gave birth to the primitive ISH. As molecular biological technology developed rapidly latter on, especially in the end of 1970s and at the beginning of 1980s when molecular cloning, plasmid and phage DNA were successfully constructed, profound technical foundation were laid to ISH.

In order to support this new technology, many institutions have themselves involved in it. In Creative BioLabs, Customers can experience the most considerable in situ hybridization (ISH) service. They offer a full array of custom in situ hybridization (ISH) service from probe design, tissue acquisition to expert interpretation of gene expression results.

Featured services of Creative Biolabs include template preparation, probe design, labeling and purification, preparation of tissue, pilot hybridization, hybridization and result interpretation. To know more about accurate and reliable In Situ Hybridization procedures, please visit

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